Grant Activities

External Funding
Project Title Agency Activity Direct Cost
NSF AIR-CREST-I/UCRC-Industry Ecosystem to Pipeline (Role: CoPI; PI: N. Rishe, Computer Science) NSF 09/2012- 6/2014 $1,000,000
The airway microbiome in COPD. (Role: CoPI; PI: Giri Narasimhan, FIU and Adam Wanner, University of Miami) Florida DOH Challenge Grant 04/10-03/12 $748,400 ($314,408 FIU Portion)
Regulation of P. aeruginosa PoxB oxacillinase by AmpR and a two-component system (Role:PI) NIH-NIGMS 04/08 – 03/12 $1,238,000
SEI+II: An integrated database approach to genome-scale analysis (Role: Co-PI; PI: Giri Narasimhan) NIH-NIGMS 04/06 – 03/08 $189,058
"Research in nanoelectronics and bio-nano sensors (II) 
(Role: Co-PI: PI: Kinzy Jones)" AFOSR 04/06 – 02/08 $400,000
"Role of Pseudomonas aeruginosa ß-lactamase genes 
(Role: PI)" NIH-NIGMS 04/05 – 03/08 $581,287
Ginseng as an antibacterial agent against Pseudomonas aeruginosa (Role: PI) NIH-R15 AREA 02/05 – 01/08 $207,075
Microbial community organization and development of a pathogenic microbial consortium  (Role: Co-Investigator; PI: L. Richardson) NIH-MBRS SCORE 02/04 – 01/08 $845,678
Development of a mold remediation process using hydrogen peroxide catalyzed by Fe(II) Ions (Role: Co-PI; PI: G. Tachiev, FIU HCET) Environmental Protection Agency 08/04 – 03/05 $92,000
Effect of ginseng on the expression of virulence factors in Pseudomonas
aeruginosa (Role: Mentor; PI: C. Bigger) NIH-MBRS MARC 04/01 – 12/05 None
Mucoid conversion of P. aeruginosa associated with chronic pulmonary infection in patients (Role: Mentor; PI: C. Bigger) NIH- MBRS RISE: R25 GM61347 04/99 – 12/05 None
Training in alternative tropical botanical medicine (Role: Co-PI; PI: B. Bennett) NIH-NCCAM 01/02 – 12/05 $1,146,485
"Regulation of b-lactamase genes of Pseudomonas aeruginosa 
(Role: PI)" NIH-MBRS SCORE 04/01 – 3/04 $482,402
Discovery and characterization of bacterial quorum sensing signals and their inhibitors (Role: Co-PI; PI: C.L. Koh) Malaysian Research Council 02 – 04 $20,000
Immuno-modulation by ginseng (Role: PI) Dansk Droge A/S, Denmark 03/02 – 09/02 $2,052
Ginseng as a possible therapeutic agent (Role: PI) Cystic Fibrosis Foundation 04/01 – 07/02 $43,200
Investigation for the effect of Chinese herb ginseng, provided by Dansk Droge A/S, on Pseudomonas aeruginosa associated with cystic fibrosis patients (Role: Co-PI; PI: A. Kharazmi) Dansk Droge A/S, Denmark 08/00 – 07/01 $37,500
Molecular biological and immunobiological strategies for prevention and treatment of P. aeruginosa from chronic lung infection in cystic fibrosis (Role: Co-PI; PI: N. Hoiby) Danish Research Council 01/98 - 12/02 $321,000
Internal Funding Internal Funding
Chemical library screening for P. aeruginosa amp pathway inhibitors (Role: PI) HWCOM-DoR 08/13 7/14 $24,000
Cystic fibrosis sputum profiling (Role: PI) FIU-NIH FREA 08/06 – 12/06 $5,000
Role of Pseudomonas aeruginosa AmpR in transcription regulation of amp genes (Role: PI) FIU-NIH FREA 07/04 – 12/04 $2,000
Phage Therapy Agents against Pseudomonas aeruginosa biofilms (Role: PI) FIU – Provost 05/04 – 09/04 $5,000
Phage Therapy Agents against Pseudomonas aeruginosa biofilms – Travel Grant (Role: PI) FIU-NIH FREA 11/03 – 12/03 $1,000
Topology analysis P. aeruginosa AmpG permease. (Role: PI) FIU-NIH FREA 10/03 – 12/03 $4,000
Investigation for the effect of Chinese herb ginseng of Pseudomonas aeruginosa (Role: PI) DSRT and A & S – Bridge Grant 04/02 – 9/02 $20,229
Undocumented soil microbes of Florida – Search for the unseen novel biosensors (Role: Co- PI; PI: K. Jayachandran ) DSRT Seed Grant 04/01 – 12/01 $4,000
Investigation for the effect of Chinese herb ginseng of Pseudomonas aeruginosa (Role: PI) DSRT Seed Grant 08/00 – 07/01 $6,000
LS50B spectrometer upgrade (Role: PI) DSRT and A & S 09/99 – 12/00 $7,185
Fellow Funding
Gorakh Tatke (PhD Student) 
Characterizing the role of MifSR two-component system proteins in regulating Pseudomonas aeruginosa metabolism NIH-BRI/MBRS Summer 2013 $3,000
Liana Apolis (Undergraduate Student)
 To identify active antiquorum-sensing compound in Bucida buceras NIH-BRI/MBRS Summer 2012 $2,000
Deepak Balasubramanian (PhD Candidate)
 Role of AmpR in Pseudomonas aeruginosa pathogenesis NIH-BRI/MBRS Summer 2011 $3,000
Diansy Zincke (PhD student)
 Regulation of the poxAB operon in Pseudomonas aeruginosa" NIH-BRI/MBRS Summer 2009 $3,000
Deepak Balasubramanian (PhD student)
 Role of AmpR in Pseudomonas aeruginosa pathogenesis" Cystic Fibrosis Foundation Jan – April 2009 $1,500
Raphael Bosse (Undergraduate) Role of PA4157 encoding an IclR-type regulator in Pseudomonas aeruginosa Cystic Fibrosis Foundation Jan – April 2009 $1,500
"Diansy Zincke (PhD student)
Function of the poxAB operon in Pseudomonas aeruginosa." NIH-BRI/MBRS Summer 2008 $3,000
Melissa Doud (PhD candidate) 
Detection of fungal organisms in the cystic fibrosis lung using amplicon length heterogeneity – polymerase chain reaction (LH-PCR). NIH-BRI/MBRS Summer 2008 $3,000
Diansy Zincke (PhD student) Regulation of Pseudomonas aeruginosa pox operon involved in oxacillin resistance. NIH- MBRS RISE Spring 2008 – ~$30,000
"Melissa Doud (PhD candidate)
 Deciphering the complex fungal and eubacterial bommunities." NIH- MBRS RISE Fall 2005 – ~$30,000
Balasubramanian Danajeyan (Visiting Scholar)
Exploitation of soil metagenomics for monitoring microbial nitrogen transformation and soil fertility. Dept of Science & Technology, India Dec 2007 – May 2008 ~$10,000
Raquel Olavarrieta (Undergraduate)
 Regulatory circuitry of Pseudomonas aeruginosa ß-lactam resistance." Cystic Fibrosis Foundation Aug – Dec 2006 $1,500
Allison Adonizio (PhD candidate)
Inhibition of quorum-sensing controlled virulence in Pseudomonas aeruginosa by southern Florida plant extracts. Cystic Fibrosis Foundation April  2006 –April 2007 $1,500
Kok-Fai Kong (PhD candidate)
Role of Pseudomonas aeruginosa AmpG in ß-lactam resistance." Cystic Fibrosis Foundation July – Sept 2005 $1,500
Krystal Anson (Undergraduate) Novel method to remediate mold. McNair Program, FIU Summer 2005 $5,000
Sixto Leal (Undergraduate) Role of Pseudomonas aeruginosa sdaA encoding L-serine deaminase in bacterial pathogenicity. Cystic Fibrosis Foundation Jan  –  Sept 2005 $1,500
Robert Sautter (MS candidate) Prc, a novel protease involved in alginate production. NIH-BRI/MBRS Summer 2005 $1,500
Allison Adonizio (PhD candidate)
Anti-quorum sensing agents from south Florida medicinal plants. NIH-BRI/MBRS Summer 2005 $3,000
Allison Adonizio (PhD candidate)
Anti-quorum sensing agents from south Florida medicinal plants and their potential to attenuate P. aeruginosa pathogenicty. Cystic Fibrosis Foundation Mar – May 2005 $1,500
Allison Adonizio (PhD candidate)
Identification of quorum sensing inhibitors in South Florida medicinal plants. NIH- MBRS RISE Summer 2005 – Spring 2008 ~$30,000
Allison Adonizio (PhD candidate)
Identification of quorum sensing inhibitors of south Florida medicinal plants: an understudied aspect of efficacy. Cystic Fibrosis Foundation Summer 2005 $1,500
Robert Smiddy (Undergraduate)
Identification of novel gene involved in mucoid conversion. NIH- MBRS RISE Spring 2004 – Fall 2004 ~$10,000
Sergio Luna (Undergraduate)
Mapping P. aeruginosa amp gene transcripts. NIH-MBRS RISE Summer 2002 –  Spring 2005 ~$10,000
Allison Adonizio (PhD candidate)
Anti-quorum sensing agents from south Florida medicinal plants. FIU 2005 $1,000
Alian Aguila (Undergraduate)
Topology analysis of Pseudomonas aeruginosa AmpG permease. NIH-MBRS MARC Spring 2002 – Spring 2003 ~$11,000