Tel: (305) 348-3082

                                                                                       Fax: (305) 348-6700

                                                                                       Office: CP 213
                                                                                       Lab:    CP 276

                                                         (Sinaia, Romania, 2005)                                     
Research InterestsbbbbRetinal image with triple band filterbbbbbbb

Experimental Biophysics
Physics of the eye and visual system: Macular pigment and its possible relationship with age-related macular degeneration; non-invasive measurement of the macular pigment; cumulative light distribution on the human retina.

Research Presentation in Cambridge, July 2013
Research Presentation in Cambridge, July 2015

Selected Publications

Bone R.A., Landrum J.T., Guerra L.H., and Ruiz C. (2003) Lutein and zeaxanthin dietary supplements raise macular pigment density and serum concentrations of these carotenoids. J. Nutr. 133, 992-998.

Krinsky N.I., Landrum J.T., Bone R.A. (2003) Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Annu. Rev. Nutr. 23, 171-201.

Bone R.A., Landrum J.T. (2004) Heterochromatic flicker photometery. Arch. Biochem. Biophys. 430, 137-142.

Bone R.A., Landrum J.T., Gibert J.C. (2004) Macular pigment and the edge hypothesis of flicker photometry. Vision Res.
44, 3045-3051.

Rosenthal J.M., Kim J., de Monastario F., Thompson D.J.S., Bone R.A., Landrum J.T., de Moura    F.F., Khachik F., Chen H., Schleicher R.L., Ferris III F.L., Chew E.Y. (2006) Dose-ranging study of lutein supplementation in persons aged 60 years or older. Invest. Ophthalmol. Vis. Sci. 47, 5227-5233.

Bone R.A., Landrum J.T., Cao Y., Howard A.N., Alvarez-Calderon F. (2006) Macular pigment response to a supplement containing meso-zeaxanthin, lutein and zeaxanthin. Nutr. Metab. 4:12.

Bone R.A., Brener B., Gibert J.C. (2007) Macular pigment, photopigments, and melanin: distributions determined by four-wavelength reflectometry. Vision Res. 47, 3259-3268.

Bone R.A. and Draper G. (2007) Optical anisotropy of the human cornea determined with a polarizing microscope. Applied Optics
46, 8351-8357.

Bone R.A., Gibert, J.C. Mukherjee, A. (2012) Light distributions on the retina: relevance to macular pigment photoprotection. Acta Biochim. Polon. 59, 167-169

Bone RA, Mukherjee A (2013) Innovative Troxler-free measurement of macular pigment and lens density with correction of the former for the aging lens. J. Biomed. Opt. 18 (10), 107003 (October 10, 2013);  doi: 10.1117/1.JBO.18.10.107003

Mukherjee A. and Bone R.A. (2016)
Lens density measurements by two independent psychophysical techniques. Eye and Vision  3:24 doi 10.1186/s40662-016-0054-6

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