2014 October

Chromevol’s study of HMG proteins published in Molecular Biology and Evolution

Posted by | Chromatin, Evolution, Research | No Comments

The results of one of our most recent projects have just been published in the latest issue of the highly influential journal “Molecular Biology and Evolution” (IF 14.308). In this paper (Evolution of High Mobility Group Nucleosome-binding -HMGN- proteins and its implications for vertebrate chromatin specialization) we focus our attention in a family of proteins known as High Mobility Group (HMG), and more specifically to those binding directly to nucleosomes in the chromatin (HMGN). Throughout this work we provide useful information to our understanding of the specialization imparted on chromatin metabolism by HMGNs, especially on the evolutionary mechanisms underlying their functional differentiation in vertebrates.

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