162.
L. Zhao, S. Doddipatla, R. I. Kaiser, W. Lu, O. Kostko, M.
Ahmed, L. B. Tuli, A. N. Morozov, A. H. Howlader, S. F.
Wnuk, A. M. Mebel, V. N. Azyazov, R. K. Mohamed, F. R.
Fischer, “Gas Phase Synthesis of Corannulene – A
Molecular Building Block of Fullerenes – in
Circumstellar Envelopes” Phys. Chem. Chem. Phys.
(Submitted)
161. M. Mudgal, D. A. Lumpuy, A.
J. Sobczak, T. P. Dang, N. Sulimoff, P. Dutta, S. Ward, K.
Ward, M. Alahmadi, A. Kumar, M. D. Sevilla, S. F. Wnuk,
and A. Adhikary, “Site of Azido Substitution in the
Sugar Moiety of Azidopyrimidine nucleosides Influences the
Reactivity of Aminyl Radicals Formed by Dissociative
Electron Attachment”, J.
Phys. Chem B. 2020,
124,
11357-11370; https://dx.doi.org/10.1021/acs.jpcb.0c08201
160. A. H. Howlader and S. F.
Wnuk, “Synthesis of iodoindenes.” Patent
Disclosure, FIU, May, 2020; D2020-0010.
159. L. Zhao, R. I. Kaiser, W.
Lu, O. Kostko, M. Ahmed, M. M. Evseev, E. K. Bashkirow, A.
D. Oleinikov, V. N. Azyazov, A. M. Mebel, A. H. Howlader,
S. F. Wnuk, “Gas Phase Formation of
Cyclopentanaphthalene (Benzindene) Isomers via Reactions
of 5- and 6-Indenyl Radicals with Vinylacetylene”. Phys
Chem Chem Phys., 2020,
22,
22493-22500. https://doi.org/10.1039/D0CP03846F
158. A. H. Howlader, K. Diaz, A.
M. Mebel, R. I. Kaiser, S. F. Wnuk, “Iodoindenes:
Synthesis and application to cross-coupling.”
Tetrahedron Lett.
2020¸ 61,1524-1527.
https://doi.org/10.1016/j.tetlet.2020.152427
157. B. P. Rosen, S. F. Wnuk,
Masafumi Yoshinaga, A. H Howlader, S. H. Suzol, “Synthesis
of the organoarsenical antibiotic arsinothricin and
derivatives thereof.” Patent Disclosure, FIU, April,
2020; D2019-0060
156. S. H. Suzol,‡
A. H. Howlader,‡
A. E. Galván, M. Radhakrishnan, S. F. Wnuk, B. P. Rosen,
and M. Yoshinaga, “Semisynthesis of the organoarsenical
antibiotic arsinothricin”. J.
Nat. Prod. 2020,
83,
2809-2813. https://dx.doi.org/10.1021/acs.jnatprod.0c00522
155. L. Zhao, R. I. Kaiser, W.
Lu, M Ahmed, A. D. Oleinikov, V. N. Azyazov, A. M. Mebel,
A. H. Howlader, S. F. Wnuk, “Gas Phase Formation of
Phenalene via 10π-Aromatic, Resonantly Stabilized Free
Radical Intermediates”. Phys
Chem Chem Phys. 2020,
22,
15381-15388. http://dx.doi.org/10.1039/D0CP02216K
154. S. F. Wnuk, M. Mudgal, I.
Nowak, M. J. Robins, “Model Substrate/Inactivation
Reactions for MoaA and Ribonucleotide Reductases: Loss of
Bromo, Chloro, or Tosylate Groups from C2 of
1,5-Dideoxyhomoribofuranoses upon Generation of an α-Oxy
Radical at C3.” Molecules
2020,
25,
2539; https://doi.org/10.3390/molecules25112539
153.
Y. Liang, Z.-W. Wen, M. de Cabrera, A. H. Howlader, S. F.
Wnuk, “Purines” in Science
of Synthesis, Knowledge
Updates 2020/1, Chapter
16.17.7; 2020,
pp 195-384. Georg Thieme Verlag KG, Stuttgart, Germany.
DOI: 10.1055/sos-SD-116-01081
152.
L. Zhao, R. I. Kaiser, W. Lu, B. Xu, M. Ahmed, A. N.
Morozov, A. M. Mebel, A. H. Howlader, S. F. Wnuk,
"Molecular Mass Growth through Ring Expansion in
Polycyclic Aromatic Hydrocarbons via Ra-dical-Radical
Reactions" Nature
Commun. (2019) 10:3689;
https://doi.org/10.1038/s41467-019-11652-5.
151. L. Zhao, M. B. Prendergast,
R. I. Kaiser, B. Xu, U. Ablikim, W. Lu, M. Ahmed, A. D.
Oleinikov, V. N. Azyazov, A. H. Howlader, S. F. Wnuk, A.
M. Mebel, "How to Add a Five-Membered Ring to
Polycyclic Aromatic Hydrocarbons (PAHs) – Molecular Mass
Growth of the 2-Naphthyl Radical (C10H7)
to Benzindenes (C13H10)
as a Case Study". Phys.
Chem. Chem. Phys. 21,
16737-16750 (2019). https://doi.org/10.1039/C9CP02930C
150. L. Zhao, M. B. Prendergast,
R. I. Kaiser, B. Xu, W. Lu, U. Ablikim, M. Ahmed, A. D.
Oleinikov, V. N. Azyazov, A. M. Mebel, A. H. Howlader, S.
F. Wnuk, "Reactivity of the Indenyl Radical (C9H7)
with Acetylene (C2H2)."
ChemPhysChem. 20,
1437-1447 (2019). DOI
10.1002/cphc.201900052
149. L. Zhao, R. I. Kaiser, B.
Xu, U. Ablikim, M. Ahmed, M. M. Evseev, E. K. Bashkirov,
V. N. Azyazov, A. N. Morozov, A. H. Howlader, S. F. Wnuk,
A. M. Mebel, D. Joshi, G. Veber, F. R. Fischer, "Gas
Phase Synthesis of [4]-Helicene via a Versatile
Vinylacetylene-Mediated Free Radical Ring Annulation."
Nature Commun. (2019)
10:1510; https://doi.org/10.1038/s41467-019-09224-8
148. Z.-W Wen, P. R. Tuttle, A.
H. Howlader, A. Vasilyeva, L. Gonzales, A. Tangar, R. Lei,
E. E. Laverde, Y. Liu, J. Miksovska, S. F. Wnuk,
"Fluorescent 5-Pyrimidine and 8-Purine Nucleosides
Modified with N-unsubstituted 1,2,3-Triazol-4-yl Moiety."
J. Org. Chem. 84,
3624-3631 (2019). https://doi.org/10.1021/acs.joc.8b03135
147. L. Zhao, B. Xu, U. Ablikim,
W. Lu, M. Ahmed, M. M. Evseev, E. K. Bashkirov, V. N.
Azyazov, A. H. Howlader, S. F. Wnuk, A. M. Mebel, R. I.
Kaiser, "Gas Phase Synthesis of Triphenylene
(C₁₈H₁₂)." ChemPhysChem.
20,
791-791 (2019). https://doi.org/10.1002/cphc.201801154
146. Z.-W. Wen, J. Peng, P. R.
Tuttle, Y. Ren, C. Garcia, D. Debnath, S. Rishi, C.
Hanson, S. Ward, A. Kumar, W. Zhao, P. M. Glazer, Y. Liu,
M. D. Sevilla, A. Adhikary, S. F. Wnuk, "Electron-mediated
Aminyl and Iminyl Radicals from C5 Azido-Modified
Pyrimidine Nucleosides Augment Radiation Damage to Cancer
Cells." Org. Lett.
20,
7400-7404 (2018).
https://doi.org10.1021/acs.orglett.8b03035
145. J. Pulido, M. de Cabrera, A.
J. Sobczak, A. Amor-Coaras, A. J. McGoron, S. F. Wnuk,
"4-N-Alkanoyl
and 4-N-Alkyl
Gemcitabine Analogues with NOTA Chelators for 68-Gallium
Labelling" Bioorg.
Med. Chem. 26,
5624-5630 (2018).
https://doi.org/10.1016/j.bmc.2018.10.007
144. Y. Liang, S. F. Wnuk, "C-H
Bond Functionalization Strategies for Modification of
Nucleosides" in Palladium-Catalyzed
Modification of Nucleosides, Nucleotides and
Oligonucleotides (Y.
Shangvi, D. Maiti, A.R.Kapdi, Eds.), Elsevier, Chapter 7,
2018; https://doi.org/10.1016/B978-0-12-811292-2.00007-6
143. V. L. Malladi, A.J. Sobczak,
L. Schneper, K. Mathee, S. F. Wnuk,
"2-Methylthiopyrrolidines and their use for
modulating bacterial quorum sensing" Patent
No.: US 9,951,007 B2; 2018
142. C. Gonzalez, M. de Cabrera,
and S. F. Wnuk, "Gemcitabine Analogues with 4-N-Alkyl
Chain Modified with Fluoromethyl Ketone Group",
Nucleosides Nucleotides
Nucleic Acids. 37,
248-260 (2018).
https://doi.org/10.1080/15257770.2018.1465186
141. L. Zhao, R. I. Kaiser, B.
Xu, M. Ahmed, M. V. Zagidullin, V. N. Azyazov, A. H.
Howlader, S. F. Wnuk and A. M. Mebel, "A VUV
Photoionization Study on the Formation of the Simplest
Polycyclic Aromatic Hydrocarbon: Naphthalene (C10H8)",
J. Phys. Chem. Lett. 9,
2620-2626 (2018).
https://pubs.acs.org/doi/pdf/10.1021/acs.jpclett.8b01020
140.
Sazzad H. Suzol, A. Hasan Howlader, Yaou Ren, Carol
Garcia, Yuan Liu, and Stanislaw F. Wnuk, "Pyrimidine
Nucleosides with Reactive (β-Chlorovinyl)sulfone or
(β-Keto)sulfone Group at C5 Position and Their
Polymerase-catalyzed Incorporation into DNA", ACS
Omega.3, 4276-4288 (2018)
https://pubs.acs.org/doi/10.1021/acsomega.8b00584
139.
C. Gonzalez, A. Sanchez, J. Collins, K. Lisova, J. T. Lee,
R. M. van Dam, M. A. Barbieri, C. Ramachandran, S. F.
Wnuk, "The 4-N-Alkyl Gemcitabine Analogues with
Silicon-Fluoride-Acceptor: Application to 18-Fluorine
Radiolabeling", Eur. J. Med. Chem. 148, 314-324
(2018);
https://doi.org/10.1016/j.ejmech.2018.02.017.
138.
M. Mudgal, S. Rishi, D. A. Lumpuy, K. A. Curran, K. L.
Verley, A. J. Sobczak, T. P. Dang, N. Sulimoff, A. Kumar,
M. D. Sevilla, S. F. Wnuk, A. Adhikary, " Prehydrated
One-Electron Attachment to Azido-Modified Pentafuranoses:
Aminyl Radical Formation, Rapid H-Atom Transfer and
Subsequent Ring Opening." J. Phys. Chem. B. 121,
4968-4980 (2017);
http://pubs.acs.org/doi/abs/10.1021/acs.jpcb.7b01838
137.
Z.-W. Wen, S. H. Suzol, J. Peng Y. Liang, R. Snoeck, G.
Andrei, S. Liekens, S. F. Wnuk, "Antiviral and
Cytostatic Evaluation of 5-(1-Halo-2-Sulfonylvinyl) and
5-(2-Furyl) Uracil Nucleosides." Arch. Pharm. Chem.
Life Sci. 350, e1700023 (2017). DOI
10.1002/ardp.201700023.
136. Q. He, L.-W. Wang,
Y. Liang, Z.-T. Zhang, S. F. Wnuk, "Transition-metal-free
cross-coupling of aryl halides with arylstannanes."
J. Org. Chem. 81, 9422-9427 (2016). DOI:
10.1021/acs.joc.6b01648.
135. S Kavoosi, R.
Rayala, B. Walsh, M. Barrios, W. G. Gonzalez, J.
Miksovska, L. Mathivathanan, R. G. Raptis, S. F. Wnuk,
"Synthesis of 8-(1,2,3-triazol-1-yl)-7-deazapurine
nucleosides by azide-alkyne click reactions and direct C-H
bond functionalization." Tetrahedron Lett. 57,
4364-4367 (2016).
http://dx.doi.org/10.1016/j.tetlet.2016.08.053
134.
C. Gonzalez, S. Kavoosi, A. Sanchez. S. F. Wnuk,
"Reduction of Sugar Lactones to hemiacetals with
Lithium Triethylborohydride." Carbohydr. Res. 432,
17-22 (2016).
http://dx.doi.org/10.1016/j.carres.2016.06.002
133.
Y. Liang, S. H. Suzol, Z. Wen, A. G. Artiles, L.
Mathivathanan, R. Raptis, S. F. Wnuk, "Uracil
Nucleosides with Reactive Group at C5 position:
5-(1-Halo-2-sulfonylvinyl)uridine Analogues." Org.
Lett. 18, 1418-1421 (2016).
http://doi:10.1021/acs.orglett.6b00346
132. R.
Rayala, A. Giuglio-Tonolo, J. Broggi, T. Terme, P.
Vanelle, P. Theard, M. Médebielle, S. F. Wnuk, "Studies
toward the oxidative and reductive activation of C-S bonds
in 2'-S-aryl-2'-thiouridine derivatives."
Tetrahedron, 72, 1969-1977 (2016).
http://dx.doi.org/10.1016/j.tet.2016.02.063
131.
C. Chbib, A J. Sobczak, M. Mudgal, C. Gonzalez, D. Lumpuy,
J. Nagaj, K. Stokowa-Soltys, S. F. Wnuk, "
S-Ribosylhomocysteine Analogues Modified at the Ribosyl
C-4 Position." J. Sulfur Chem. 37, 307-327 (2016).
http://dx.doi.org/10.1080/17415993.2015.1137921
130.
A. J. Sobczak, C. Chbib, S. F. Wnuk,
"S-Ribosylhomocysteine Analogs Containing a
[4-Thio]ribose Ring." Carbohydr. Res. 415, 39-47
(2015). http://doi:10.1016/j.carres.2015.07.005
129.
J. Zayas, M. Annoual, J. K. Das, Q. Felty, W. G. Gonzalez,
J. Miksovska, N. Sharifai, A. Chiba, S. F. Wnuk, "Strain
Promoted Click Chemistry of 2- or 8-Azidopurine and
5-Azidopyrimidine Nucleosides and 8-Azidoadenosine
Triphosphate with Cyclooctynes. Application to Living Cell
Fluorescent Imaging." Bioconjug. Chem. 26, 1519-1532
(2015). http://doi:10.1021/acs.bioconjchem.5b00300
128.
Y. Liang, S. F. Wnuk, "Modification of Purine and
Pyrimidine Nucleosides by Direct C-H Bond Activation"
Molecules, 20, 4874-4901 (2015).
http://doi:10,3390/molecules20034874
127. A.
Adhikary, A. Kumar, R. Rayala, R. M. Hindi, A. Adhikarya,
S. F. Wnuk , M. D. Sevilla, "A One-electron oxidation
of Gemcitabine and analogs: Mechanism of formation of C3′
and C2′ sugar radicals." J. Am. Chem. Soc. 136,
15646-15653 (2014).
http://pubs.acs.org/doi/pdf/10.1021/ja5083156n
126.
R. Rayala, P. Theard, H. Ortiz, S. Yao, J. D. Young, J.
Balzarini, M. J. Robins, S. F. Wnuk, "Synthesis of
Purine and 7-Deazapurine Nucleoside Analogues of
6-N-(4-Nitrobenzyl)adenosine; Inhibition of Nucleoside
Transport and Proliferation of Cancer Cells."
ChemMedChem. 9, 2186-2192 (2014).
http://dx.doi.org/10.1002/cmdc.201402047
125.
Y. Liang, J. Gloudeman, S. F. Wnuk, "Palladium-Catalyzed
Direct Arylation of 5-Halouracils and 5-Halouracil
Nucleosides with Arenes and Heteroarenes Promoted by
TBAF." J. Org. Chem. 79, 4094-4103 (2014).
http://dx.doi.org/10.1021/jo500602p
124.
M. Zhu, Z.-T. Zhang, D. Xue, H. Hua, Y. Liang, S. F. Wnuk,
" Synthesis of 1-Amino-3-cyano-5,6-diaryl-2-pyridones
and 6,7-diaryl-4-Cyano-3-hydroxy-1H-1,2-diazepines from
Isoflavones" Helv. Chim. Acta. 97, 561-568, (2014).
http://onlinelibrary.wiley.com/doi/10.1002/hlca.201300246/abstract
123.
A. Díaz, E. Martínez, L. Puerta, D. Méndez, E.
Rodríguez, L. Fang, S. Wnuk, R. Vivas-Reyes, "CoMSIA
study to design antagonist ligands for LuxS protein"
New J. Chem. 38, 1235-1249 (2014).
http://dx.doi.org/10.1039/c3nj01162c
122.
J. Pulido, A. Sobczak, J. Balzarini, S. F. Wnuk,
"Synthesis and Cytostatic Evaluation of 4-N-Alkanoyl
and 4-N-Alkyl Gemcitabine Analogues." J. Med. Chem.
57, 191-203 (2014).
http://dx.doi.org/10.1021/jm401586a
121.
M. Zhu, . Z.-T. Zhang, D. Xue, J. Qiao, Y. Liang, S. F.
Wnuk, "Synthesis of 5,6-Diaryl-2-pyridones from
Isoflavones." Chin. J. Chem. 31, 1027-1032, (2013).
http://dx.doi.org/10.1002/cjoc.201300279.
120.
Y. Liang, J.-P. Pitteloud, S. F. Wnuk, "Hydrogermylation
of 5-ethynyluracil nucleosides: Formation of
5-(2-germylvinyl)uracil and 5-(2-germylacetyl)uracil
nucleosides." J. Org. Chem. 78, 5761-5767, (2013)
http://dx.doi.org/10.1021/jo400590z
119.
A. Adhikary, A. Kumar, A. N. Heizer, B. J. Palmer, V.
Pottiboyina, Y. Liang, S. F. Wnuk, M. D. Sevilla,
"Hydroxyl ion addition to one-electron oxidized
thymine: Unimolecular interconversion of C5 to C6
OH-adducts." J. Am. Chem. Soc. 135, 3121-3234 (2013);
http://dx.doi.org/10.1021/ja310650n
118.
V. L. Malladi, L. Schneper , A.J. Sobczak, K. Mathee, S.
F. Wnuk, "2-Methylthiopyrrolidines and their use for
modulating bacterial quorum sensing" Patent WO
2012/174511 A1.
117. T. P. Dang, A. J. Sobczak,
A. M. Mebel, C. Chatgilialoglu, S. F. Wnuk, "Investigation
of reactions postulated to occur during inhibition of
ribonucleotide reductases by
2'-azido-2'-deoxynucleotides." Tetrahedron,68,
5665-5667 (2012).
http://dx.doi.org/10.1016/j.tet.2012.04.050
116.
A. Shokar, A Au, S. H. An, E. Tong, G. Garza, J. Zayas, S.
F. Wnuk, K. M. Land, "Adenosylhomocysteine hydrolase
of the protozoan parasite Trichomonas vaginalis: Potent
inhibitory activities of
9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine."
Bioorg. Med. Chem. Lett. 22, 4203-4205 (2012).
http://dx.doi.org/10.1016/j.bmcl.2012.03.0817
115.
R. Rayala, S. F. Wnuk, "Bromination at C-5 of
Pyrimidine and C-8 of Purine Nucleosides with
1,3-Dibromo-5,5-dimethylhydantoin." Tetrahedron Lett.
53, 3333-3336 (2012).
http://dx.doi.org/10.1016/tetlet.2012.04.081
114.
S. F. Wnuk, J. A. K. Penjarla, T. Dang, A. M. Mebel, T.
Nauser, C. Schöneich, "Modeling of the
Ribonucleotide Reductases Substrate Reaction. Hydrogen
Atom Abstraction by a Thiyl Free Radical and Detection of
the Ribosyl-based Carbon Radical by Pulse Radiolysis.
Coll. Czech. Chem. Commun. 76, 1223-1238 (2011).
113.
V. L. Malladi, A. J. Sobczak, T. M. Meyer, D. Pei, S. F.
Wnuk, " Inhibition of LuxS by S-Ribosylhomocysteine
Analogues Containing a [4-Aza] Ribose Ring." Biorg.
Med. Chem. 19, 5507-5519 (2011).
112. V. L.
Malladi, A.J. Sobczak, N. Maricic, S. K. Murugapiran, L.
Schneper, J. Makemson, K. Mathee, S. F. Wnuk, "Substituted
Lactam and Cyclic Azahemiacetals Modulate Pseudomonas
aeruginosa Quorum Sensing." Biorg. Med. Chem. 19,
5500-5506 (2011).
111. J.-P. Pitteloud, Y.
Liang, S. F. Wnuk, "Chemoselective transfer of Allyl
or Phenyll Group from Allyl(phenyl)germanes in
Pd-catalyzed Reactions with Aryl Halides." Chem.
Lett. 40, 967-969 (2011).
110. J.-P. Pitteloud,
Z-T. Zhang, Y. Liang, L. Cabrera, S. F. Wnuk, "
Fluoride-Promoted Cross-Coupling of Chloro(mono-, di-, or
triphenyl)germanes with Aryl Halides in "Moist"
Toluene. Multiple Transfer of the Phenyl Group from
Organogermane Substrates and Comparison of the Coupling
Efficiencies of Chloro(phenyl)germanes with their
Corresponding Stannane and Silane Counterparts." J.
Org. Chem. 75, 8199-8212 (2010).
109. P. J.
Dornbush, G. Vazquez-Anaya, A. Shokar, S. Nguyen, M. Rapp,
S.F. Wnuk, L.A. Wrischnik, K.M. Land. AdoHcy Hydrolase of
Trichomonas vaginalis: Studies of the effects of
5'-modified adenosine analogues and related
6-N-cyclopropyl derivatives." Bioorg. Med. Chem.
Lett. 20, 7466-7468 (2010).
108. Z-T. Zhang,
J.-P. Pitteloud, L. Cabrera, Y. Liang, M. Turibio, S. F.
Wnuk, "Arylchlorogermanes/TBAF/"Moist"
toluene: A promosing combination for Pd-catalyzed
Germyl-Stille Cross-coupling" Org. Let. 10, 816-819
(2010).
107. S. F. Wnuk, J. Robert, B. P.
Meyers, A. J. Sobczak, J. Zhu, B. Gopishetty, D. Pei, "
Inhibition of S-ribosylhomocysteinase (LuxS) by Substrate
Analogues Modified at the Ribosyl C-3 Position"
Bioorg. Med. Chem. 17, 6699-6706 (2009).
106.
P. R. Sacasa, J. Zayas, S. F. Wnuk, "
Radical-mediated thiodesulfonylation of the vinyl
sulfones: Access to (a-fluoro)vinyl
sulfides", Tetrahedron Lett. 50, 5424-5427
(2009).
105. S. F. Wnuk, P. R. Sacasa, J.
Restrepo, "Application of germyldesulfonylation
reactions to the synthesis of germanium-containing
nucleoside analogues" Nucleosides Nucleotides &
Nucleic Acids, 24, 537-549 (2009).
104. P. K.
R. Nair, S. J. Melnick, S. F. Wnuk, M. Rapp, E. Escalon,
C. Ramachandran, "Isolation and Characterization of
an Anticancer Catechol Compound from Semecarpus
anacardium", J. Ethnopharmacol. 124, 450-456
(2009).
103. M. Rapp, X. Cai, W. Xu, W. R.
Dolbier, Jr., S. F. Wnuk, "Reactions of
fluorosulfonyldifluoroacetate with Purine and Pyrimidine
Nucleosides", J. Fluorine Chem. 130, 321-328
(2009).
102. B. Gopishetty, J. Zhu, R. Rajan,
A. Sobczak, S. F. Wnuk, C. E. Bell, D. Pei, "Probing
the Catalytic Mechanism of S-Ribosylhomocysteinase (LuxS)
with Catalytic Intermediates and Substrate Analogues"
J. Am. Chem. Soc. 131, 1243-1250 (2009).
101.
H. Zipse, E. Artin, S. F. Wnuk, G. J. S. Lohman, D.
Martino, R. G. Griffin, S. Kacprzak, M. Kaupp, B. Hoffman,
M. Bennati, J. Stubbe, N. Lees, "Structure of the
nucleotide radical formed during reaction of CDP/TTP with
the E441Q-a2β2
of E. coli ribonucleotide reductase" J. Am. Chem.
Soc. 131, 200-211 (2009).
100. S. F. Wnuk, P.
R. Sacasa, E. Lewandowska, D. Andrei, S. Cai, R. T.
Borchardt, "Synthesis of 5'-functionalized
nucleosides: S-Adenosylhomocysteine analogues with the
Carbon-5' and Sulfur Atoms Replaced by a Vinyl or
Halovinyl Unit" Bioorg. Med. Chem. 16, 5424-55433
(2008).
99. S. F. Wnuk, J. Lalama, C. A.
Garmendia, J. Robert, J. Zhu, D. Pei,
"S-ribosylhomocysteine analogues with the carbon-5
and sulfur atoms replaced by a vinyl or (fluoro)vinyl
unit", Bioorg. Med. Chem. 16, 5090-5102 (2008).
98.
Z. Wang, J.-P. Pitteloud, L. Montes, M. Rapp, D. Derane,
S. F. Wnuk, "Vinyl Tris(trimethylsilyl)silanes:
Substrates for Hiyama Coupling", Tetrahedron. 64,
5322-5327 (2008).
97. S. F. Wnuk, P. R. Sacasa,
"(p-Toluenesulfonylmethylene)triphenylphosphorane"
in Electronic Encyclopedia of Reagents for Organic
Synthesis, Paquette, L. A., Crich, D. Eds; Wiley, 2008.
DOI 10.1002/047084289X.rn00884.
96. S. F. Wnuk,
J. Lalama, J. Robert, C. A. Garmendia, "Novel
S-ribosylhomocysteine analogues as potential inhibitors of
LuxS enzyme", Nucleosides Nucleotides Nucleic Acids.
26, 1051-1055 (2007).
95. M. J. Robins, I.
Nowak, S. F. Wnuk, F. Hansske, Danuta Madej,
"Deoxygenative [1,2]-Hydride Shift Rearrangements in
Nucleoside and Sugar Chemistry: Analogy with the
[1,2]-Electron Shift in the Deoxygenation of
Ribonucleotides by Ribonucleotide Reductases", J.
Org. Chem. 72, 8216-8221 (2007).
94. W. Xu, K.
A. Abboud, I, Ghiviriga, W. R. Dolbier, Jr., M. Rapp, S.
F. Wnuk, "An unexpected reaction of trimethylsilyl
fluorosulfonyldifluoroacetate (TFDA) with imidazoles.
Formation of N-difluoromethyl- thioureas", Org. Lett.
8, 5549-5551 (2006).
93. D. Andrei, S. F. Wnuk,
"S-Adenosylhomocysteine Analogues with the Carbon-5'
and Sulfur Atoms Replaced by a Vinyl Unit", Org.
Lett. 8, 5093-5096 (2006).
92. S. F. Wnuk, J.
M. Robins, "Ribonucleotide Reductase Inhibitors as
Anti-Herpes Agents" Antiviral. Res. 71, 122-126
(2006).
91. M. Rapp, T. A. Haubrich, J.
Perrault, Z. B. Mackey, J. H. McKerrow, P. K. Chiang,S. F.
Wnuk, "Antitrypanosomal Activity of 6'-Iodohomovinyl
Derivatives of Adenosine and Related
6-N-Cyclopropyladenosine Analogues", J. Med. Chem.
49, 2096-2102 (2006).
90. D. Andrei, S. F.
Wnuk, "Synthesis of the Multisubstituted Halogenated
Olefins via Cross-Coupling of Dihaloalkenes with Alkylzinc
Bromides" J. Org. Chem. 71, 405-408 (2006).
89.
M. J. Robins, S. F. Wnuk, "Reduction of
Ribonucleosides to 2'-Deoxynucleosides" in Current
Protocols in Nucleic Acid Chemistry, Jones, R. A., Ed.;
John Wiley & Sons, New York, NY, 2005; Supplement 21,
Unit 1.11.
88. Z. Wang, A. Gonzalez, S. F.
Wnuk, "Pd-catalyzed couplings of (a-fluoro)vinyl
tris(trimethylsilyl)germanes", Tetrahedron Lett. 46,
5313-5316, (2005).
87. J. Fritscher, E. Artin,
S. F. Wnuk, G. Bar, J. H. Robblee, S. Kacprzak, M. Kaupp,
R. G. Griffin, M. Bennati, J. Stubbe, "Structure of
the nitrogen-centered radical formed during inactivation
of E. coli ribonucleotide reductase by
2'-azido-2'-deoxyuridine-5'-diphosphate: trapping of the
3'-ketonucleotide", J. Am. Chem. Soc. 127, 7729-7738,
(2005).
86. M. Wang, J. Zhang, D. Andrei, K.
Kuczera, R. T. Borchardt, S. F. Wnuk, "Are
L-Adenosine and its Derivatives Substrates for
S-Adenosyl-L-homocysteine Hydrolase?", J. Med. Chem.
48, 3649-3653, (2005).
85. Z. Wang, S. F. Wnuk,
"Application of Vinyl Tris(trimethylsilyl)germanes in
Pd-catalyzed Couplings", J. Org. Chem. 70, 3281-3284
(2005).
84. J.-L. Décout, S. F. Wnuk,
"Sugar-modified thionucleosides: Chemistry and
inhibition of ribonucleotide reductases and
S-adenosyl-L-homocysteine hydrolases" in Frontiers in
Nucleic Acids, Schinazi, R. F. and Liotta, D. C., Eds.;
IHL Press, Atlanta, GA, 2004, pp. 235-265.
83.
P. K. R. Nair, S. Rodriguez, R. Ramachandran, A. Alamo, S.
J. Melnick, E. Escalon, P. I. Garcia Jr., S. F. Wnuk, C.
Ramachandran , "Immune stimulatory properties of a
novel polysaccharide for biodefense from the medicinal
plant Tinospora cordifolia", International
Immunopharmacol. 4, 1645-1659 (2004).
82. S. F.
Wnuk, E. Lewandowska, P. R. Sacasa, L. N. Crain, J. Zhang,
R. T. Borchardt, E. De Clercq, "Stereoselective
Synthesis of Sugar-Modified Enyne Analogues of Adenosine
and Uridine. Interaction with S-Adenosyl-L-homocysteine
Hydrolase, and Antiviral and Cytotoxic Effects", J.
Med. Chem. 47, 5251-5257, (2004).
81. S. F.
Wnuk, P. I. Garcia, Jr., Z. Wang, "Radical-mediated
Silyl- and Germyldesulfonylation of Vinyl and
(a-Fluoro)vinyl
Sulfones and Application of Tris(trimethylsilyl)silanes
and germanes in Pd-catalyzed Couplings", Org. Lett.
6, 2101-2104 (2004).
80. C. Chatfield, A.
Augusten, C. D'Cunha, E. Lewandowska, S. F. Wnuk,
"Theoretical and experimental study of the
regioselectivity of Michael addition", Eur. J. Org.
Chem. 313-322 (2004).
79. S. F. Wnuk, D. R.
Companioni, E. Lewandowska, P. I. Garcia Jr., J. A.
Secrist III, "Synthesis and cytotoxicity of
9-(2-deoxy-2-alkyldithio-b-D-arabinofuranosyl)purine
nucleosides which are stable precursors to potential
mechanistic probes of ribonucleoside reductases",
Org. Biomol. Chem. 2, 120-126 (2004).
78. E.
Lewandowska, J. Lalama, C.-S. Yuan, S. F. Wnuk,
"Open-Chain Carboacyclic Analogs of Adenosine with
Dihalovinyl Unit as Potential Inhibitors of
S-Adenosyl-L-Homocysteine Hydrolase", Nucleosides
Nucleotides Nucleic Acids 22, 1747-1755 (2003).
77.
S. F. Wnuk, P. R. Sacasa, L. N. Crain, E. Lewandowska, J.
Zhang, R. T. Borchardt, "Stereocontrolled Synthesis
of Diene and Enyne Sugar-Modified Nucleosides and their
Interaction with S-Adenosyl L-homocysteine Hydrolase",
Nucleosides Nucleotides Nucleic Acids 22, 783-785
(2003).
76. S. F. Wnuk, D. Companioni, V.
Neschadimenko, M. J. Robins, "The b-Fluorine
Effect. Electronic versus Steric Effects in Radical
Deoxygenation of Fluorine-Containing Pentofuranose
Nucleosides", J. Org. Chem. 67, 8794-8797
(2002).
75. C. Merryman, E, Weinstein, S. F.
Wnuk, D. P. Bartel, "A Biofunctional tRNA for in
vitro Protein Selection", Chem. Biol. 9, 741-746
(2002).
74. S. F. Wnuk, B.-O. Ro, C. A. Valdez,
E. Lewandowska, N. X. Valdez, P. R. Sacasa, D. Yin, J.
Zhang, R. T. Borchardt, E. De Clercq, "Sugar-Modified
Conjugated Diene Analogues of Adenosine and Uridine.
Synthesis, Interaction with S-Adenosyl-L-homocysteine
Hydrolase and Antiviral and Cytostatic Effects", J.
Med. Chem. 45, 2651-2658 (2002).
73. S. F.
Wnuk, L. A. Bergolla, P. I. Garcia, Jr., "Studies
Towards Synthesis of a-Fluorinated
Phosphonates via Tin-Mediated Cleavage of a-Fluoro
a-(pyrimidin-2-ylsulfonyl)
alkylphosphonates. Intramolecular cyclization of
a-phosphonyl
radicals", J. Org. Chem. 67, 3065-3071 (2002).
72.
E. Lewandowska, S. Kinastowski, S. F. Wnuk "Studies
on the Rearrangement of ortho-Nitrobenzylidenemalonates
and Their Analogues to 2-Aminobenzoate Derivatives"
Can. J. Chem. 80, 192-199 (2002).
71. S. F.
Wnuk, S. M. Chowdhury, P. I. Garcia, M. J. Robins,
"Stereodefined Synthesis of O3'-Labeled Uracil
Nucleosides. 3'[17O]-Labeled 2'-Azido-2'-deoxyuridine
5'-Diphosphate as a Probe for the Mechanism of
Inactivation of Ribonucleotide Reductases", J. Org.
Chem. 67, 1816-1819 (2002).
70. M. J. Robins,
J. S. Wilson, D. Madej, D. L. J. Tyrrel, W. P. Gati, R. J.
Lindmark, S. F. Wnuk, "Nucleic Acid Related
Compounds. 114. Synthesis of 2,6-(Disubstituted)purine
2',3'-dideoxynucleosides and selected Cytotoxic,
Anti-Hepatatis B, and Adenosine Deaminase Substrate
Activities", J. Heterocycl. Chem. 38, 1297-1306
(2001).
69. S. F. Wnuk, "Targeting
'Hydrolytic' Activity of the S-Adenosyl-L-homocysteine
Hydrolase", Mini-Review Med. Chem. 1, 307-316
(2001).
68. S. F. Wnuk, C. A. Valdez, N. X.
Valdez, "Rhodium(I)-Catalyzed Regio- and
Stereoselective Chloroesterification Of Furanose-derived
Terminal Alkynes With Ethyl Chloroformate", J.
Carbohydr. Chem. 20, 71-79 (2001).
67. X. Yang,
D. Yin, S. F. Wnuk, M. J. Robins, R. T. Borchardt
"Mechanism of Inactivation of human
S-Adenosylhomocysteine Hydrolase by
5',5',6',6'-Tetradehydro-6'-deoxy-6'-halohomoadenosines"
Biochemistry 80, 15234-15241 (2000).
66. S. F.
Wnuk, E. Lewandowska, C. A. Valdez, S. Kinastowski
"Rearrangement of Nitropyridylidene-malonate
1-Oxides. A Novel Method for the Synthesis of
Aminopyridine Derivatives" Tetrahedron 56, 7667-7671
(2000).
65. S. F. Wnuk, J. M. Rios, J. Khan,
Y.-L. Hsu "Synthesis of a-Fluoro
Esters via Stannyl Radical-Mediated Cleavage of
p-Deficient
Heterocyclic Sulfones" J. Org. Chem. 65, 4169-4174
(2000).
64. S. F. Wnuk, C. A. Valdez, J. Khan,
P. Moutinho, M. J. Robins, X. Yang, R. T. Borchardt, J.
Balzarini, E. De Clercq "Doubly Homologated
Dihalovinyl and Acetylene Analogues of Adenosine.
Synthesis, Interaction with S-Adenosyl-L-homocysteine
Hydrolase, and Antiviral and Cytostatic Effects" J.
Med. Chem. 43, 1180-1186 (2000).
63. S. F.
Wnuk, C.-S Yuan, R. T. Borchardt, M. J. Robins. "Design
and Biological Evaluation of New Mechanism-Based
Inhibitors of S-Adenosyl-L-homocysteine Hydrolase"
Nucleosides & Nucleotides 18, 595-596, (1999).
62.
Z. Guo, M. C. Samano, J. W. Krzykawski, S. F. Wnuk, G. J.
Ewing, M. J. Robins "Biomimetic Modeling of the
Abstraction of H3' by Ribonucleotide Reductases.
1,5-Hydrogen Atom Transfer of H3 to Aminyl and Oxyl, but
not Thiyl, Free Radicals in Homoribofuranose Derivatives"
Tetrahedron 55, 5705-5700 (1999).
61. J.
Giziewicz, S. F. Wnuk, M. J. Robins "Nucleic Acid
Related Compounds. 107. Efficient Nitration of Uracil Base
and Nucleoside Derivatives" J. Org. Chem. 64,
2149-2151 (1999).
60. M. J. Robins, Z. Guo, M.
C. Samano, S. F. Wnuk "Biomimetic Simulation of Free
Radical-Initiated Cascade Reactions Postulated to Occur at
the Active Site of Ribonucleotide Reductases" J. Am.
Chem. Soc. 121, 1423-1433 (1999).
59. Z.
Karolewski, P. Golinski, S. Wnuk, O. Li, Z. Weber
"Chemical and Biological Characteristics of
Metabolite of Non-Aggressive Phoma Lingam (Tode Ex. Fr.)
Desm. Isolate" Phytopathol. Pol. 15, 15-23
(1998).
58. M. J. Robins, E. Lewandowska, S. F.
Wnuk, "Nucleic Acid Related Compounds. 105. Synthesis
of 2',3'-Didehydro-2',3'-Dideoxynucleosides from
Ribonucleoside Cyclic 2',3'-(Sulfates or Phosphates) or
2',3'-Dimesylates Via Reductive Elimination with Sodium
Naphthalenide", J. Org. Chem. 63, 7375-7381
(1998).
57. M. J. Robins, S. F. Wnuk, X. Yang,
C.-S. Yuan, R. T. Borchardt, J. Balzarini, E. De Clercq,
"Inactivation of S-Adenosyl-L-homocysteine Hydrolase
and Antiviral Activitiy with
5',5',6',6'-Tetradehydro-6'-Deoxy-6'-Halohomoadenosine
Analogues (4'-Haloacetylene Analogues Derived from
Adenosine)" , J. Med. Chem. 41, 3857-3864
(1998).
56. S. F. Wnuk, Y. Mao, C.-S Yuan, R.
T. Borchardt, G. Andrei, J. Balzarini, E. De Clercq, M. J.
Robins, "Discovery of Type II (Covalent) Inactivation
of S-Adenosyl-L-homocysteine Hydrolase. Synthesis and
Evaluation of Dihalohomovinyl Nucleoside Analogues Derived
from Adenosine", J. Med. Chem. 41, 3078-3083
(1998).
55. C.-S Yuan, S. F. Wnuk, M. J.
Robins, R. T. Borchardt, "A Novel Mechanism-Based
Inhibitor
(6'-bromo-5',6'-didehydro-6'-deoxy-6'-fluorohomoadenosine)
That Covalently Modifies Human Placental
S-Adenosylhomocysteine Hydrolase", J. Biol. Chem.
273, 18191-18197 (1998).
54. M. J. Robins, S.
Sarker and S. F. Wnuk, "What Are the Practical Limits
for Detection of Minor (Nucleoside) Reaction Products with
HPLC (UV), 1H NMR, and TLC?", Nucleosides &
Nucleotides, 17, 785-790 (1998).
53. S. F.
Wnuk, C.-S. Yuan, R. T. Borchardt and M. J. Robins,
"Synthesis of Homologated Halovinyl Derivatives from
Aristeromycin and their Inhibition of Human Placental
S-Adenosyl-L-homocysteine hydrolase", Nucleosides &
Nucleotides, 17, 99-113 (1998).
52. M. J.
Robins, V. Neschadimenko, B.-O Ro, C-S. Yuan, R. T.
Borchardt and S. F. Wnuk, "Nucleic Acid Related
Compounds. 101. S-Adenosyl-L-homocysteine Hydrolase Does
Not Hydrate (5'-Fluoro)vinyl or (6'-Halo)homovinyl
Analogues Derived from 3'-Deoxyadenosine or 3'-(Chloro or
Fluoro)-3'-deoxyadenosine", J. Org. Chem., 63,
1205-1211 (1998).
51. M. J. Robins, R. Zou, F.
Hansske and S. F. Wnuk, "Synthesis of sugar-modified
2,6-diaminopurine and guanine nucleosides from guanosine
via transformations of 2-aminoadenosine and enzymatic
deamination with adenosine aminohydrolase", Can. J.
Chem., 75, 762-767 (1997).
50. H. Huang, C.-S
Yuan, S. F. Wnuk, M. J. Robins and R. T. Borchardt, "The
mechanism of inactivation of human placental
S-Adenosylhomocysteine hydrolase by
(E)-4',5'-didehydro-5'-methoxyadenosine (DMAO) and
adenosine 5'-carboxaldehyde oxime (ACAO)", Arch.
Biochem. Biophys., 343, 109-117 (1997).
49. S.
F. Wnuk, C.-S. Yuan, R. T. Borchardt, J. Balzarini, E. De
Clercq and M. J. Robins, "Anticancer and Antiviral
Effects and Inactivation of S-Adenosyl-L-homocysteine
Hydrolase with 5'-Carboxaldehydes and Oximes Synthesized
from Adenosine and Sugar-Modified Analogues", J. Med.
Chem., 40, 1608-1618 (1997).
48. E.
Lewandowska, V. Neshchadimenko, S. F. Wnuk and M. J.
Robins, "Efficient Removal of Sugar O-Tosyl Groups
and Heterocycle-Halogens from Nucleosides with Sodium
Naphthalenide", Tetrahedron, 53, 6295-6302
(1997).
47. M. J. Robins, Z. Guo and S. F.
Wnuk, "Elimination of Chlorine (Radical) or Tosylate
(Anion) from C2' of Nucleoside C3' Free Radicals as Model
Reactions Postulated To Occur at the Active Site of
Ribonucleotide Reductases", J. Am. Chem. Soc., 119,
3637-3638 (1997).
46. M. J. Robins, S. Sarker,
V. Samano and S. F. Wnuk, "Nucleic Acid Related
Compounds. 94. Remarkably High Stereoselective Reductions
of 2'- and 3'-Ketonucleoside Derivatives to Give Arabino,
Ribo, and Xylofuranosyl Nucleosides with Hydrogen Isotopes
at C2' and C3'", Tetrahedron, 53, 447-456
(1997).
45. M. J. Robins, R. Zou, Z. Guo and S.
F. Wnuk, "Nucleic Acid Related Compounds. 93. A
Solution for the Historic Problem of Regioselective
Sugar–Base Coupling To Produce 9-Glycosylguanines or
7-Glycosylguanines", J. Org. Chem., 61, 9297-9212
(1996).
44. M. J. Robins, S. F. Wnuk, A. E.
Hernandez and M. C. Samano, "Nucleic Acid Related
Compounds. 91.Biomimetic Reactions are in Harmony with
Loss of 2'-Substituents as Free Radicals (Rather than
Anions) During Mechanism-Based Inactivation of
Ribonucleotide Reductases. Differential Interactions of
C2' Azide, Halogen, and Alkylthio Groups With
Tributylstannane and Triphenylsilane", J. Am. Chem.
Soc., 118, 11341-11348 (1996).
43. M. J.
Robins, Z. Guo, M. C. Samano and S. F. Wnuk, "Biomimetic
Modeling of the Decomposition of
2'-Chloro-2'-deoxynucleotides by Ribonucleotide Reductases
to Give 3(2H)-Furanones Which Can Effect Mechanism-Based
Inactivation by Michael-Type Alkylation", J. Am.
Chem. Soc., 118, 11317-11318 (1996).
42. S. F.
Wnuk, S. Liu, C.-S Yuan, R. T. Borchardt and M. J. Robins,
"Inactivation of S-Adenosyl-L-homocysteine Hydrolase
by Amide and Ester Derivatives of Adenosine-5'-Carboxylic
Acid", J. Med. Chem., 39, 4162-4166 (1996).
41.
C.-S Yuan, S. Liu, S. F. Wnuk, M. J. Robins and R. T.
Borchardt, "Design and Synthesis of
S-Adenosylhomocysteine Hydrolase Inhibitors as
Broad-Spectrum Antiviral Agents", in Advances in
Antiviral Drug Design, De Clercq, E., Ed.; JAI Press,
1996, Vol 2, pp 41-88.
40. S. F. Wnuk and M. J.
Robins, "Stannyl Radical-Mediated Cleavage of
p-Deficient
Heterocyclic Sulfones. Synthesis of a-Fluoro
Esters and the First Homonucloside a-Fluoromethylene
Phosphonate", J. Am. Chem. Soc., 118, 2519-2520
(1996).
39. M. J. Robins, J. S. Wilson, D.
Madej, N. H. Low, F. Hansske and S. F. Wnuk, "Nucleic
Acid Related Compounds. 88. Efficient Conversions of
Ribonucleosides into their 2',3'-Anhydro, 2'(and
3')-Deoxy, 2',3'-Didehydro-2',3'-dideoxy, and
2',3'-Dideoxynucleoside Analogues", J. Org. Chem.,
60, 7902-7908 (1995).
38. M. J. Robins, S. F.
Wnuk, “Antimony(III) Chloride”, in Encyclopedia of
Reagents for Organic Synthesis, Paquette, L. A., Ed.; John
Wiley & Sons: Chichester, 1995, Vol. 1, pp
205-206.
37. C.-S Yuan, S. Liu, S. F. Wnuk, M.
J. Robins and R. T. Borchardt, "Rational Approaches
to the Design of Mechanism-Based Inhibitors of
S-Adenosyl-homocysteine Hydrolase", Nucleosides
Nucleotides 14, 439-447 (1995).
36. M. J.
Robins, S. F. Wnuk, "Selected Aspects of the
Chemistry and Biochemistry of Sulfur-Containing
Nucleosides", Phosphorus, Sulfur, Silicon Relat.
Elem. 95/96, 71-88 (1994).
35. G. Wenska, B.
Skalski, S. Paszyc, S. Wnuk, R. W. Adamiak "Fluorescent
Nucleoside Derivatives: Luminescence Study of
4-Dimethylamino-pyridinium Chloride Derived from
Guanosine" J. Fluorescence 4, 283-286 (1994).
34.
C.-S Yuan, S. F. Wnuk, S. Liu, M. J. Robins, and R. T.
Borchardt
"(E)-5',6'-Didehydro-6'-Deoxy-6'-Fluorohomoadenosine:
A Substrate that Measures the Hydrolytic Activity of
S-Adenosylhomocysteine Hydrolase", Biochemistry 33,
12305-12311 (1994).
33. S. F. Wnuk, "Synteza
5'-Fluorowych Analogow S-Adenozylohomocysteiny oraz innych
5'-Modyfikowanych Nukleozydow i ich Aktywnosc
Biologiczna", (Synthesis of the 5'-Fluoro Analogues
of S-Adenosylhomocysteine and other 5'-Modified
Nucleosides and their Biological Acticity) Roczniki
Akademii Rolniczej w Poznaniu, Rozprawy Naukowe: Zeszyt
(issue) #251, (1994).
32. S. F. Wnuk, C.-S.
Yuan, R. T. Borchardt, J. Balzarini, E. De Clercq and M.
J. Robins, "Nucleic Acid Related Compounds. 84.
Synthesis of 6'(E and Z)-Halogenohomovinyl Derivatives of
Adenosine, Inactivation of S-Adenosyl-L-homocysteine
Hydrolase, and Correlation of Anticancer and Antiviral
Potencies with Enzyme Inhibition", J. Med. Chem., 37,
3579-3587 (1994).
31. S. F. Wnuk, J. D.
Stoeckler and M. J. Robins, "Nucleic Acid Related
Compounds. 82. Conversion of Adenosine to Inosine
5'-Thioether Derivatives with Aspergillus Oryzae Adenosine
Deaminase or Alkyl Nitrites. Substrate and Inhibitory
Activities of Inosine 5'-Thioether Derivatives with Purine
Nucleoside Phosphorylase", Nucleosides Nucleotides,
13, 389-403 (1994).
30. C.-S Yuan, S. Liu, S.
F. Wnuk, M. J. Robins and R. T. Borchardt, "Mechanism
of Inactivation of S-Adenosylhomocysteine Hydrolase by
(E)-5',6'-Didehydro-6'-Deoxy-6'-Halo-Homoadenosines",
Biochemistry 33, 3758-3765 (1994).
29. M. J.
Robins, S. F. Wnuk, K. B. Mullah, N. K. Dalley, C.-S.
Yuan, Y. Lee and R.T. Borchardt, "Nucleic Acid
Related Compounds. 80. Synthesis of 5'-S-(Alkyl and
aryl)-5'-fluoro-5'-thioadenosines with Xenon Difluoride or
(Diethylamino)sulfur Trifluoride, Hydrolysis in Aqueous
Buffers, and Inhibition of S-Adenosyl-L-homocysteine
Hydrolase by Derived 'Adenosine 5'-Aldehyde' Species",
J. Org. Chem., 59, 544-555 (1994).
28. S. F.
Wnuk, "Sulfur and Seleno-Sugar Modified Nucleosides.
Synthesis, Chemical Transformation and Biological
Properties", Tetrahedron, 49, 9877-9936 (1993).
27.
M. J. Robins and S. F. Wnuk, "Efficient Conversions
of Thioethers to a-Fluoro
Thioethers with DAST or DAST/Antimony(III) Chloride",
J. Org. Chem., 58, 3800-3801 (1993).
26. S.
Liu, S. F. Wnuk, C. Yuan, M. J. Robins and R. T.
Borchardt, "Adenosine 5'-Carboxaldehyde: A Potent
Inhibitor of S-Adenosyl-L-homocysteine Hydrolase", J.
Med. Chem., 36, 883-887 (1993).
25. S. F. Wnuk
and M. J. Robins, "Nucleic Acid Related Compounds.
78. Stereocontrolled syntheses of 6'(E and Z)-halovinyl
analogues from uridine-derived vinylsulfones via vinyltin
intermediates", Can. J. Chem., 71, 192-198
(1993).
24. S. F. Wnuk, N. K. Dalley and M. J.
Robins, "Nucleic Acid Related Compounds. 76.
Synthesis of 5'(E and
Z)-Chloro-4',5'-didehydro-5'-deoxyadenosines via
Chlorination and Thermolysis of Adenosine 5'-Sulfoxides.
Mechanism-Based Inhibition of S-Adenosyl-L-homocysteine
Hydrolase", J. Org. Chem., 58, 111-117 (1993).
23.
M. J. Robins, S. F. Wnuk, K. B. Mullah, N. K. Dalley, R.
T. Borchardt, Y. Lee and C.-S. Yuan, "Adenosine-Derived
5'-a-Halo
Thioether, Sulfoxide, Sulfone, and (5'-Halo)methylene
analogues. Inhibition of S-Adenosyl-L-Homocysteine
hydrolase", in Nucleosides and Nucleotides as
Antitumor and Antiviral Agents (C. K. Chu, D. C. Baker,
Eds.), Plenum Press, New York, p. 115-126, 1993.
22.
M. J. Robins, K. B. Mullah, S. F. Wnuk and N. K. Dalley,
"Nucleic Acid Related Compounds. 73. Fluorination of
Uridine 2'-Thioethers with Xenon Difluoride or
Diethylaminosulfur Trifluoride. Synthesis of Stable
2'-Alkyl (or Aryl)sulfonyl-2'-deoxy-2'-fluorouridines",
J. Org. Chem., 57, 2357-2364 (1992).
21. M. J.
Robins, S. D. Hawrelak, A. E. Hernandez and S. F. Wnuk,
"Nucleic Acid Related Compounds. 71. Efficient
general synthesis of purine (amino, azido, and
triflate)-sugar nucleoside", Nucleos. Nucleot., 11,
821-834 (1992).
20. M. J. Robins, S. F. Wnuk,
K. B. Mullah and N. K. Dalley, "Nucleic Acid Related
Compounds. 68. Fluorination at C5' of Nucleside
5'-Thioethers with DAST/Antimony(III) Trichloride or Xenon
Difluoride to give 5'-S-Aryl-5'-fluoro-5'-thiouridines",
J. Org. Chem., 56, 6878-6884 (1991).
19. S. F.
Wnuk, N. K. Dalley and M. J. Robins, "Nucleic Acid
Related Compounds. 67. Synthesis of 5'-amino and
5'-methylthio chain-extended nucleosides from uridine",
Can. J. Chem., 69, 2104-2111 (1991).
18. M. J.
Robins, F. Hansske, S. F. Wnuk and T. Kanai, "Nucleic
Acid Related Compounds. 66. Improved syntheses of
5'-chloro-5'deoxy- and 5'-S-aryl(or
alkyl)-5'-thionucleosides", Can. J. Chem., 69,
1468-1474 (1991).
17, S. F. Wnuk and M. J.
Robins, "Nucleic Acid Related Compounds. 63.
Synthesis of 5'-deoxy-5'-methyleneadenosine and related
Wittig-extended nucleosides", Can. J. Chem., 69,
334-338 (1991).
16. S. F. Wnuk and M. J.
Robins, "Reactivity of Uridine 5'-Silylphosphites in
Arbuzov Reactions", Roczniki Akademii Rolniczej w
Poznaniu CCXXIII, 61-69 (1991).
15. S.
Kinastowski, E. Kaczmarek, S. Wnuk, "The
Rearrangement of ortho-Nitro-benzylidenemalonates
Derivatives in Reaction with Thiols", Pol. J. Chem.
64, 595-605 (1990).
14. S. F. Wnuk and M. J.
Robins, "Antimony(III) Chloride Exerts Potent
Catalysis of the Conversion of Sulfoxides to a-Fluoro
Thioethers with (Diethylamino)sulfur Trifluoride", J.
Org. Chem., 55, 4757-4760 (1990).
13. E.
Kaczmarek, S. Wnuk, S. Kinastowski, "Some Critical
Remarks on the Synthesis of 2,4-Dinitrobenzaldehyde",
Roczniki Akademii Rolniczej w Poznaniu 210, 29-37
(1990).
12. S. Wnuk, E. Wyrzykiewicz, E.
Kaczmarek, S. Kinastowski, "Carbon-13 Chemical Shift
Assignments of Derivatives of Benzoic Acid", Magn.
Reson. Chem. 28, 271-280 (1990).
11. S.
Kinastowski, S Wnuk, E. Kaczmarek, "Synthesis of
2,4-dinitro- and 2,4,6-Trinitrobenzylidene Compounds by
Knoevenagel Condensation", Pol. J. Chem. 63, 495-503
(1989).
10. M. J. Robins and S. F. Wnuk
"Fluorination at C5' of Nucleosides. Synthesis of the
New Class of 5'-Fluoro-5'-S-Aryl(Alkyl)thionucleosides
from Adenosines", Tetrahedron Lett. 29, 5729-5732
(1988).
9. P. Golinski, S. Wnuk, J. Chelkowski,
M. Schollenberger "Formation of Avenacein Y by
Fusarium avenaceum Fries Sacc. Isolates from Poland and
Biological Properties of the Compound" Mycotoxins
Research, Special Edition, European Seminar
'Fusarium-mycotoxins, taxonomy, pathogenicity', (Warsaw
1987), 49-52 (1988).
8. P. Golinski, S. Wnuk,
M. Manka, P. Lepom, M. Kloss, "Formation of Avenacein
Y by Fusarium avenaceum Fries Sacc. Isolates from Germany
and Pathogenicity of the Isolates to Cereal Seedling",
Mycotoxins Research, Special Edition, European Seminar
'Fusarium-mycotoxins, taxonomy, pathogenicity', (Warsaw
1987), 46-48 (1988).
7. S. Kinastowski, S.
Wnuk, E. Kaczmarek, "The Rearrangement of
ortho-Nitrobenzylidenemalonate Derivatives in Reactions
with Amines. Applications to Organic Synthesis",
Synthesis 111-118 (1988).
6. C. P.
Gorst-Allman, P. H. van Rooyen, S. Wnuk, P. Golinski, J.
Chelkowski, "Structural elucidation of an antibiotic
from the fungus Fusarium avenaceum Fries Sacc., an amended
structure for laterpyrone", S. Afr. J. Chem. 39,
116-117 (1986).
5. P. Golinski, S. Wnuk, J.
Chelkowski, A. Visconti, M. Schollenberger, "Antibiotic
Y: Biosynthesis by Fusarium avenaceum (Corda ex Fries)
Sacc., Isolation, and Some Physicochemical and Biological
Properties", Appl. Environ. Microbiol. 51, 743-745
(1986).
4. J. Slawinski, S. Wnuk, "Wplyw
promieniowania UV na aktywnosc hemoproteidow w modelowym
ukladzie luminol-H2O2-OH", (The influence of
UV-Radiation on the activity of hemoproteins in the model
system luminol-H2O2-OH) Zeszyty Problemowe Postepu Nauk
Rolniczych PAN 271, 307-313 (1984).
3. S.
Kinastowski, S. Wnuk, "2,4-Dinitrobenzaldehyd in
Knoevenagel Condensation", Pol. J. Chem. 57, 625-627
(1983).
2. S. Wnuk, S. Kinastowski, E.
Kaminski, "Synthesis and analysis of 1-octen-3-ol,
the main flavour component in mushrooms", Nahrung 27,
479-486 (1983).
1. S. Kinastowski, S. Wnuk, "A
Convenient One-Step Synthesis of Ethyl 2-[N-
(Diethoxycarbonyl)(ethoxy)-methyl]amino-4-nitrobenzoate
and Analogues by Rearrangement of
2,4-Dinitrobenzylidenemalonates", Synthesis 654-659
(1983).
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