Omics

Congrats to Vicky Suarez-Ulloa on completing a great PhD!!!

Posted by | DNA, Epigenetics, FIU, Graduate student, Marine Biology, Omics, Oysters, Red Tides, Research, Toxicology | No Comments

Victoria Suarez-Ulloa defended her PhD dissertation last week with perfect scores!, this completes a very productive stage in her academic trajectory with 10 papers published, several presentations in international conferences and most importantly, a postdoctoral position already lined up in Europe to continue working with population epigenomics. Vicky, we’re really proud of you and wish you the best for the future!!!

Our last work has been just published today on Peer J!

Posted by | Bioinformatics, DNA, Marine Biology, Omics, Red Tides, Research, Toxicology | No Comments

Victoria (Vicky) Suarez-Ulloa, a Graduate Student at Chromevol, has led our last paper entitled “Unbiased high-throughput characterization of mussel transcriptomic responses to sublethal concentrations of the biotoxin okadaic acid”, published today in the journal Peer J. In this work we have collaborated with researchers from UK and Spain characterizing the genes involved in responses to the effects of marine biotoxins. In the pictures below you can see the now traditional “hanging ceremony” of the paper reprint below the corresponding poster (presented at the Gordon Conference in Ecological and Evolutionary Genomics last summer) in the hallway near our lab. Vicky was fortunate enough to count with the help and indications of three gentleman during this operation.

Congrats!!!

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Graduate Students wanted!

Posted by | Education, Epigenetics, FIU, Histones, Marine Biology, Omics, Research | No Comments

Graduate Student (PhD) positions available in Dr. Eirin-Lopez’s Chromatin Structure & Evolution Lab (Department of Biological Sciences, Florida International University) starting in Fall 2016.

We are looking for enthusiastic, dynamic and independent students broadly interested in studying the interface between evolution, epigenetics and adaptation in marine organisms. Students would ideally have a B.S. degree in Biology or related discipline (academic training in biology, statistics, genetics and evolution) and must be proficient in English (both spoken and written). Candidates with additional knowledge on computer science and/or bioinformatics are encouraged to apply. Our research addresses the study of chromatin and epigenetics from different perspectives, most notably evolution, development and adaptation. To this end we use marine invertebrates as model systems in the lab, as well as a wide range of eukaryote groups in molecular evolutionary analyses. Our current projects combine elements from marine biology, toxicology, molecular biology, biochemistry, next generation sequencing, bioinformatics and molecular evolution to address environmental problems in the oceans. Our work requires good organizational and computational skills and the ability to work collaboratively as part of a team. Detailed information about our research is available at our website (chromevol.com). Follow us in Facebook (facebook.com/chromevol) and Twitter (@chromevol)

Potential research topics include (but are not limited to):

1) Characterization of epigenetic mechanisms underlying environmental responses and adaptation in marine invertebrates. This research addresses the roles of DNA methylation, histone variant modifications and other epigenetic mechanisms during responses to environmental stressors, notably by using bivalve molluscs and corals as model organisms.

2) Development of high-throughput “-omic” tools improving pollution biomonitoring in coastal areas. This topic focuses on the development of methods that can be routinely used to identify early exposure of marine organisms to genotoxic pollutants (e.g., microarrays, qPCR, proteomic analyses, etc.), specially in the case of commercially relevant shellfish, marine mammals and other megafauna.

3) Molecular evolutionary and phylogenetic analysis of chromosomal proteins in metazoans. This objective builds on the molecular evolutionary tradition of our group, studying the mechanisms governing the diversification/differentiation of gene and protein families across eukaryotes and their consequences for organismal evolution.

Related research topics are also welcome. Interested students will be required to apply to the Graduate Program in the Dept. of Biological Sciences at FIU (http://biology.fiu.edu/graduate/). Acceptance in the lab will be subject to successful application for Teaching Assistantship funds (TAs). Interested students are also strongly encouraged to apply for graduate research fellowships (e.g., National Science Foundation Graduate Research Fellowship). In order to be considered, qualified candidates must submit a statement of interest, curriculum vitae, unofficial transcripts (GPA scores), GRE scores, TOEFL scores (if applicable) and summary of research interests in a single PDF file to Dr. Eirin-Lopez (jeirinlo@fiu.edu). To receive full consideration, applications and required materials should be received as soon as possible, and never later than November 30th.

 

See ad with more details here.

Personalized epigenetics and the future of health sciences

Posted by | Bioinformatics, Epigenetics, FIU, Omics, Research | No Comments

The latest publication resulting from our ongoing collaboration with the Bioinformatics Research Group (BioRG) at FIU’s School of Computing & Information Sciences is now available!. In this work (Computational methods in epigenetics), BioRG’s postdoc Dr. Vanessa Aguiar-Pulido (L) and Chromevol’s graduate student Victoria Suarez-Ulloa (R) lead a revision describing the main characterisitics of the various types of data generated during epigenetic studies, providing a description of the most common computational approaches used for their integrative analysis. Congratulations for such a wonderful job!

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Environmental epigenetics meets marine invertebrates

Posted by | Chromatin, DNA, Epigenetics, Histones, Marine Biology, Omics, Toxicology | No Comments

Environmental epigenetics investigates the cause-effect relationships between specific environmental factors and the subsequent epigenetic modifications triggering adaptive responses in the cell. Given the dynamic and potentially reversible nature of the different types of epigenetic marks, environmental epigenetics constitutes a promising venue for developing fast and sensible biomonitoring programs. Indeed, several epigenetic biomarkers have been successfully developed and applied in traditional model organisms (e.g., human and mouse). Nevertheless, the lack of epigenetic knowledge in other ecologically and environmentally relevant organisms has hampered the application of these tools in a broader range of ecosystems, most notably in the marine environment.

Fortunately, that scenario is now changing thanks to the growing availability of complete reference genome sequences along with the development of high-throughput DNA sequencing and bioinformatic methods. Altogether, these resources make the epigenetic study of marine organisms (and more specifically marine invertebrates) a reality.

vicky_600x400rodri_600x400We have built on this knowledge to develop a review/perspectives paper on this topic, recently published in the journal Marine Pollution Bulletin. This work (conducted by Victoria Suarez-Ulloa and Rodrigo Gonzalez-Romero, grad student and postdoc at Chromevol, respectively) provides a timely perspective highlighting the extraordinary potential of environmental epigenetic analyses as a promising source of rapid and sensible tools for pollution biomonitoring, using marine invertebrates as sentinel organisms. This strategy represents an innovative, groundbreaking approach, improving the conservation and management of natural resources in the oceans.

 

Marine Sciences Seminar on Florida Red Tides

Posted by | DNA, Education, FIU, Omics | No Comments

This Friday we are closing the 2015 edition of the “Worlds Ahead Marine Sciences Seminar Series” with the visit of Dr. Emily Monroe from the Dept. of Biology at William Patterson University. In this opportunity, Dr. Monroe will be presenting the seminar “Polyketide Synthase Gene Expression in the Florida Red Tide Dinoflagellate, Karenia brevis.

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The seminar will take place on Friday May 1st, at 12 pm in MSB-105 (BBC campus). In case anyone wants to attend from MMC, please send me an email to arrange polycom broadcast. Also, please contact me in case you want to meet with Dr. Monroe, there will be plenty of opportunities to interact either before or after the seminar.

As you know, Florida Red Tides constitute a major threat in our coastal areas, causing neurotoxic shellfish poisoning in marine organisms, affecting aquaculture and fishery industries, as well as producing respiratory distress in humans. Since many FIU folks develop active research on different aspects of this dinoflagellate species, this seminar promises to be a great framework for interaction, discussion and hopefully future collaborations!

Overall, a great closing for this year’s seminar series!!!. Many thanks to FIU’s University Graduate School, the Dept. of Biological Sciences, the Dept. of Chemistry and Biochemistry and the Marine Sciences Program for their support. Many thanks to our graduate students for selecting a great representation of top notch speakers for these seminars and to all the speakers who visited our beautiful Miami.

Finally, special thanks to all of YOU who attended the seminars and the social events associated with them. Remember, THAT is what gives this seminar series a reason to be alive for future editions and new generations of students.

We look forward to seeing y’all next year! have a great summer!

Thanks to Dr. Steven Roberts for his visit and a great seminar last week at FIU

Posted by | Chromatin, DNA, Education, Evolution, FIU, Omics | No Comments

Last week we had the visit of Dr. Steven Roberts as our invited speaker within the “2015 Worlds Ahead Marine Sciences Seminar Series”. In addition to enjoying a great seminar, we had the chance of exchanging many exciting ideas about future projects addressing the epigenetic basis of environmental responses and adaptation in marine invertebrates. Many thanks Steven!

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Marine Sciences seminar on DNA methylation by Dr. Steven Roberts (UWashington)

Posted by | Chromatin, DNA, FIU, Omics, Research | No Comments

Next week we’ll have the visit of Dr. Steven Roberts as invited speaker within FIU’s “2015 Worlds Ahead Marine Sciences Seminar Series”. Dr. Roberts is an Associate Professor in the School of Aquatic and Fishery Sciences at the University of Washington (http://faculty.washington.edu/sr320/), where his research focuses on characterizing physiological responses of marine organisms to environmental change. In his seminar he will provide clues to answer the following question: “Does DNA methylation facilitate phenotypic plasticity in marine invertebrates?“.

We really think it does!!

The Chromevol group has many common interests with Dr. Roberts’ research goals! we really look forward to his seminar! The date is Thursday April 23rd at 12pm and the place is room MSB-105 at BBC Campus. The seminar will be followed by a “end-of-semester” BBQ, you’re all invited!

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16th Annual Biology Research Symposium held at BBC campus

Posted by | Awards, Education, Omics, Research | No Comments
The Annual BioSymposium of FIU’s Department of Biological Sciences was held on Saturday February 1st at the Marine Science Building of the Biscayne Bay Campus (where our lab is located). Graduate students from our Department showcased their work in exciting talks and poster presentations, illustrating the extraordinary quality of the research developed in our Department. As a special note, we want to congratulate our own Victoria Suarez-Ulloa for obtaining the 2nd position in the best talk presentation award with the presentation “CROMEVALOAdb: a data mining approach to the study of chromatin in bivalves”.
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